A random sample of SCC tumors from our TMAs were selected to calculate tumor staging using our linear regression model when considering only E-cadherin score.

The tables show the score for phospho-Rb S249, p39, E-cadherin and the patient´s tumor stage (first fourth columns, respectively). The fifth column shows the stage predicted by our linear regression analysis only when considering E-cadherin. The Error (sixth) columns in all five tables show the difference between the vendor score and our linear regression analysis score, a value of 0 indicating identical scores, while a number other than 0 means that the two scores were different by a magnitude equal to the number indicated in the column. E-cadherin was unable to accurately predict stage in 7 out of 7 samples.