Thyroid hormone receptor is essential for larval eptiehlial apoptosis and adult epithelial stem cell development

Our experiment revealed that TR double knockout completely blocks intestinal length shortening, larval cell death, and adult stem cell development, demonstrating a requirement for TR in adult intestinal development. Overall design: Compare the thyroid hormone target gene expression with or without thyroid hormone receptor in the intestine during metamorphosis climax of Xenopus tropicalis