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MSL2 reads DNA shape to distinguish X from autosome for dosage compensation. MSL2 reads DNA shape to distinguish X from autosome for dosage compensation

NIAID Data Ecosystem2026-03-09 收录

染色体剂量

DNA形状识别

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA302262 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2015-11-16

染色体剂量

组蛋白甲基化调控

In Drosophila, two chromosomes require special mechanisms to balance their transcriptional output to the rest of the genome. These are the male-specific lethal complex targeting the male X chromosome

NIAID Data Ecosystem120

Drosophila MSL complex selectively identifies active genes on the male X chromosome

基因表达调控

染色体剂量

X-chromosome dosage compensation in Drosophila requires the male-specific lethal (MSL) complex, which up-regulates gene expression from the single male X chromosome. Here, we define X-chromosome-speci

NIAID Data Ecosystem60

Deconvolving the recognition of DNA shape from sequence

转录因子结合

DNA形状识别

Binding of transcription factors to DNA is mediated by the recognition of the chemical signatures of the DNA bases and the three-dimensional shape of the DNA molecule. The direct contribution of DNA

NIAID Data Ecosystem40

MSL2 reads DNA shape to distinguish X from autosome for dosage compensation (SXL RNAi in Kc cells experiments)

剂量补偿

DNA形状识别

The rules according to which transcription factors selectively bind only a small subset of genomic sites from a vast pool of similar sequences are not understood. One of the most challenging tasks in

NIAID Data Ecosystem120

Sex-dimorphic gene expression and ineffective dosage compensation of Z-linked genes in gastrulating chicken embryos. Gallus gallus

生物性别决定机制

染色体剂量

Sex determination is still poorly understood in birds and no key determinants have so far been identified. In contrast to most other species, dosage compensation of bird sex chromosomal genes appears

NIAID Data Ecosystem40

MSL2 reads DNA shape to distinguish X from autosome for dosage compensation. MSL2 reads DNA shape to distinguish X from autosome for dosage compensation

资源简介：

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