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Core components of the nuclear pore bind distinct states of chromatin and contribute to Polycomb repression

NIAID Data Ecosystem2026-03-11 收录

核孔复合体与染色质调控

Polycomb机制

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE136117 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2020-01-07

植物表观遗传学

Polycomb机制

Polycomb repressive complex 1 (PRC1) and PRC2 are chromatin regulators maintaining transcriptional repression by depositing H2A mono-ubiquitination (H2Aub) or H3 lysine 27 tri-methylation (H3K27me3),

NIAID Data Ecosystem60

Variant PCGF1-PRC1 links PRC2 recruitment with induced transcriptional inactivation at target genes [ChIP-seq]

Polycomb机制

胚胎干细胞分化

Polycomb repressive complexes-1 and -2 (PRC1 and 2), silence developmental genes in spatiotemporally regulated manner during metazoan embryogenesis. How PcG proteins contribute to down-regulation of t

NIAID Data Ecosystem40

hnRNPK recruits PCGF3/5-PRC1 to the Xist RNA B-repeat to establish Polycomb mediated chromosomal silencing. hnRNPK recruits PCGF3/5-PRC1 to the Xist RNA B-repeat to establish Polycomb mediated chromosomal silencing

Polycomb机制

XistRNA调控

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem20

p300/CBP sustains Polycomb silencing by non-enzymatic functions (ChIP-seq on RNAi-treated Drosophila S2 cells). p300/CBP sustains Polycomb silencing by non-enzymatic functions (ChIP-seq on RNAi-treated Drosophila S2 cells)

Polycomb机制

CBP非酶功能

Maintenance of appropriate cell states involves epigenetic mechanisms, including Polycomb group (PcG)-mediated transcriptional repression. While PcG proteins are known to induce chromatin compaction,

NIAID Data Ecosystem40

Polycomb repression works without Siesta [ChIP]

Polycomb机制

H2A泛素化

Polycomb group proteins are essential for epigenetic repression of developmental genes. They act as multi-subunit complexes whose biochemical functions are yet to be fully characterised. One of the co

NIAID Data Ecosystem30

Core components of the nuclear pore bind distinct states of chromatin and contribute to Polycomb repression

资源简介：

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