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Proteomics of Extracellular Vesicles from hiPSC-Derived Cardiac Organoids

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NIAID Data Ecosystem2026-05-10 收录
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Human cardiac organoids were derived from hiPSCs using a regimen of small molecules and morphogens. Extracellular vesicles (cardEVs) were subsequently isolated from the conditioned medium via differential centrifugation. Finally, the proteomic cargo of cardEVs was characterized using LC-MS/MS and bioinformatically compared against EVs derived from the AC10 cardiomyocyte cell line and cadaveric human heart explants (heEVs).

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2026-02-02
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