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Transcriptome analysis of desmoplastic small round cell tumors identifies actionable therapeutic targets: a report from the Children's Oncology Group

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NIAID Data Ecosystem2026-03-11 收录
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The oncoprotein encoded by EWS-WT1, the hallmark diagnostic alteration in DSRCT, binds to FGFR4 and IGF2. JN-DSRCT-1 cells were subjected to chromatin immunoprecipitation using antibodies against RNA polymerase-II (positive cotnrol), the c-terminus of WT1 (to precipitate the EWS-WT1 fusion protein), or IgG (negative control)

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2020-08-18
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