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Gene expression profiles of WT and epithlial GSDMD ko mouse intestine [scRNA-seq]

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE289524
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The small intestine (SI) is the first site of absorption for life-sustaining nutrients and a gateway for external pathogens and toxins. Diet enables the host to initiate the SI absorptive machinery, while maintaining the barrier activity and a strict immune homeostasis. To uncover the role of epithelial GSDMD in SI physiology, we conditionally deleted Gsdmd in intestinal epithelial cells by generating Villin-cre+; Gsdmdf/f (GsdmdΔIEC) mice
创建时间:
2025-08-07
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