Stone matrix phase preferring protein list.

The list of the top 60 most highly abundant and highly prevalent proteins found in CaOx stone matrix (from Table 2 in [reference 8]) was reduced by removing 7 proteins, including UROM (uromodulin), EGF (epidermal growth factor), APOD (apolipoprotein D), ALBU (albumin), IGKC (Ig kappa chain C region), IGHG1 (Ig gamma-2 chain C) and IPSP (plasma serine protease inhibitor) that were found at higher relative abundance in urine than in stone matrix. Additionally, ubiquitin was also removed from this list due to an ambiguous definition of this protein in updated protein databases, leaving 52 proteins that were found to be enriched in CaOx stone matrix in [Reference 8]. The abbreviations, accession numbers, and protein names are given for each protein, as well as the number of aspartate (D), glutamate (E), arginine (R), and lysine (K) residues in each protein, listed as both absolute totals and percentages for each amino acid. Total charge and net charge were calculated for each protein as described in the Methods section, and each was listed as both absolute totals and percentages for these 52 proteins. A column containing updated accession numbers for 3 proteins which had changed from the original publication has been added. (XLSX)