Rapid estrogen receptor signaling is essential for the protective effects of estrogen against vascular injury

ChEBI2012-09-01 更新2026-07-21 收录

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血管损伤保护机制

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-35558 数据链接链接失效反馈

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Rapid estrogen receptor signaling is essential for the protective effects of estrogen against vascular injury

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2012-09-01

Aorta- and liver-specific ERalpha-binding patterns and gene regulation by estrogen (ChIP-seq)

组织特异性表观遗传学

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Estrogen has vascular protective effects in premenopausal women and in women under 60 receiving hormone replacement therapy. However, estrogen also increases risks of breast and uterine cancers and of

NIAID Data Ecosystem100

Analysis of estrogen-induced mRNA in endometrial cancer cells with forced expression of ER. Analysis of estrogen-induced mRNA in endometrial cancer cells with forced expression of ER

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子宫内膜癌转录组分析

We used the endometrial adenocarcinoma cell line in which the ERα cDNA gene was transfected and forcedly expressed ER. Then the factors induced by estrogen (Estradiol: E2) were measured by microarray.

NIAID Data Ecosystem50

Dietary ligands diindolylmethane and resveratrol result in diverse ERα signaling not seen after E2 and a subset of diindolylmethane mediated signaling needs concurrent AHR activation.. Dietary ligands diindolylmethane and resveratrol result in diverse ERα signaling not seen after E2 and a subset of diindolylmethane mediated signaling needs concurrent AHR activation.

乳腺癌分子机制

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Inhibitory crosstalk between estrogen receptor alpha (ER alpha ) and aryl hydrocarbon receptor (AHR) regulates 17-estradiol (E2)-dependent breast cancer cell signaling. ER alpha and AHR are transcript

NIAID Data Ecosystem40

MDFIC alteration of the GR transcriptome in COS-1 cells depends on S211 phosphorylation of GR

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转录组调控

Glucocorticoids are primary stress hormones that regulate many physiological processes, and synthetic derivatives of these molecules and are widely used in the clinic. The cellular response to glucoc

NIAID Data Ecosystem50

Temporal transcriptional response from primary human chronic lymphocytic leukemia (CLL)-cells after B-cell receptor stimulation.

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慢性淋巴细胞白血病转录组

The B-cell receptor (BCR) signaling is crucial for the pathophysiology of most leukemias and lymphomas originated from mature B lymphocytes and has emerged as a new therapeutic target, especially for

NIAID Data Ecosystem40

Rapid estrogen receptor signaling is essential for the protective effects of estrogen against vascular injury

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