These high-depth meta-Hi-C chromatin contact matrices are surprisingly powerful in capturing long-range functional relationships of chromatin interactions, which are now able to predict coexpression,
Additional file 7:Co-expressed gene pairs have more Hi-C interactions than all pairs. T tests are used to test the difference between Hi-C interactions of co-expressed gene pairs and all pairs. In co-
It is essential to regulate the expression of genes, such as those encoding the proteins of the cardiac sarcomere. This regulation is often mediated by cis regulatory elements termed enhancers and rep
Additional file 1: Table S1. Datasets used in this study. (A) data availability (B) QC statistics of Micro-C, Hi-C, and promoter capture Micro-C data (C) Additional metrics of promoter capture Micro-C