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Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei in complex with 5'-iodo-cytosine

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Protein Data Bank Japan2024-02-21 更新2026-03-21 收录
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Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei in complex with 5'-iodo-cytosine Descriptor: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 5'-deoxy-5'-iodocytidine, CHLORIDE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2009-09-30 Release date: 2009-10-13 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics, 12, 2011

本数据集收录类鼻疽伯克霍尔德菌(Burkholderia pseudomallei)来源的2-C-甲基-D-赤藓醇-2,4-环二磷酸合酶(2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase)与5'-脱氧-5'-碘胞苷(5'-deoxy-5'-iodocytidine)结合的晶体结构。数据集描述项包括:2-C-甲基-D-赤藓醇-2,4-环二磷酸合酶、5'-脱氧-5'-碘胞苷、氯离子(CHLORIDE ION)等。作者为西雅图传染病结构基因组学中心(Seattle Structural Genomics Center for Infectious Disease, SSGCID)。提交日期:2009年9月30日;发布日期:2009年10月13日;最后修改日期:2024年2月21日。实验方法:X射线衍射(X-RAY DIFFRACTION),解析分辨率为1.85埃(Å)。引用文献:《利用片段筛选结合结构解析靶向传染病药物靶点:类鼻疽伯克霍尔德菌MECP合酶》,发表于《结构与功能基因组学杂志(Journal of Structural and Functional Genomics)》,2011年,第12卷。
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2009-09-30
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