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Structural basis of activation of the tumor suppressor protein neurofibromin

NIAID Data Ecosystem2026-03-13 收录

蛋白质结构生物学

肿瘤抑制机制

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资源简介：

Full gel picture for FigS1 of Chaker-Margot et al. 2022 Structural basis of activation of the tumor suppressor protein neurofibromin

应用场景：

创建时间：

2022-03-21

细胞染色质动态

肿瘤抑制机制

Cellular senescence is a stable proliferation arrest that suppresses tumorigenesis. Histone chaperone HIRA deposits nucleosome-destabilizing histone variant H3.3 into chromatin in a DNA replication-in

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Structure of the minimal Ste5 VWA domain subject to autoinhibition by the Ste5 PH domain

蛋白质结构生物学

信号传导调控

Structure of the minimal Ste5 VWA domain subject to autoinhibition by the Ste5 PH domain Descriptor: Protein STE5 Authors: Coyle, S.M, Zalatan, J.G, Lim, W.A. Deposit date: 2012-05-07 Release date: 20

Protein Data Bank Japan2023-09-13 更新70

PLTP is a p53 target gene with roles in cancer growth suppression and ferroptosis

肿瘤抑制机制

铁死亡调控

The tumor suppressor protein p53 suppresses cancer by regulating processes such as apoptosis, cell cycle arrest, senescence, and ferroptosis. Whereas numerous p53 target genes have been identified, o

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Common Tumor Suppressive Signaling of Thyroid Hormone Receptor Beta in Breast and Thyroid Cancer Cells

肿瘤抑制机制

转录组学分析

The thyroid hormone receptor beta (TRÃ) is a tumor suppressor in multiple types of solid tumors, most prominently in breast and thyroid cancer. An increased understanding of the molecular mechanisms

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FtsA (apo form) from Thermotoga maritima

蛋白质结构生物学

细胞分裂机制

FtsA (apo form) from Thermotoga maritima

NIAID Data Ecosystem50