Inactive S1A/N269D-cpPvdQ mutant in complex with the pyoverdine precursor PVDIq reveals a specific binding pocket for the D-Tyr of this substrate
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Inactive S1A/N269D-cpPvdQ mutant in complex with the pyoverdine precursor PVDIq reveals a specific binding pocket for the D-Tyr of this substrate Descriptor: Acyl-homoserine lactone acylase PvdQ, N-[(1R)-1-{(6S)-6-[(2-amino-2-oxoethyl)carbamoyl]-1,4,5,6-tetrahydropyrimidin-2-yl}-2-(4-hydroxyphenyl)ethyl]-N~2~-tetradecanoyl-L-glutamine Authors: Mascarenhas, R, Catlin, D, Wu, R, Clevenger, K, Fast, W, Liu, D. Deposit date: 2016-12-20 Release date: 2017-03-01 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Circular Permutation Reveals a Chromophore Precursor Binding Pocket of the Siderophore Tailoring Enzyme PvdQ To Be Published
与荧光嗜铁素(pyoverdine)前体PVDIq结合的失活型S1A/N269D-cpPvdQ突变体,揭示了该底物D-酪氨酸(D-Tyr)的特异性结合口袋。
描述对象:酰基高丝氨酸内酯酰化酶(Acyl-homoserine lactone acylase)PvdQ,N-[(1R)-1-{(6S)-6-[(2-氨基-2-氧代乙基)氨基甲酰基]-1,4,5,6-四氢嘧啶-2-基}-2-(4-羟基苯基)乙基]-N₂-肉豆蔻酰-L-谷氨酰胺
作者:Mascarenhas R, Catlin D, Wu R, Clevenger K, Fast W, Liu D
提交日期:2016年12月20日
发布日期:2017年3月1日
最后修改日期:2024年11月13日
实验方法:X射线衍射法(X-RAY DIFFRACTION,分辨率2.55埃(Å))
引用文献:《环置换(Circular Permutation)揭示嗜铁素(siderophore)修饰酶PvdQ的生色团前体结合口袋》(待发表)
创建时间:
2016-12-20



