Additional file 2 of Definitive-intent uniform megavoltage fractioned radiotherapy protocol for presumed canine intracranial gliomas: retrospective analysis of survival and prognostic factors in 38 cases (2013–2019)

Additional file 2: Figure a. Right frontal glioma. A, B: Pre-treatment T2-WI (A), T1-WI + (B). C,D: Two months post-RT. T2-WI (C), T1-WI + (D). These images show complete response with disappearance of contrast-enhancement. Figure b. Right piriform glioma. A,B: Pre-treatment T2-WI (A), T1-WI+ (B). Absence of contrast enhancement. C,D: 2 months post-RT. T2-WI (C), T1-WI+ (D). These images show PR/SD with decreased T2-WI hyperintensity, according to RECIST criteria for non-enhancing tumour. Figure c: Left piriform glioma. A,B: Pre-treatment T2-WI (A), T1-WI+ (B). C,D: Four months post-RT. T2-WI (C), T1-WI + (D). These images show partial response with persistent diffuse contrast enhancement (dotted arrow).附加文件2：图a 右侧额叶胶质瘤。A、B：治疗前T2加权成像（T2-weighted imaging, T2-WI）（A）、T1加权增强成像（T1-weighted imaging with contrast enhancement, T1-WI+）（B）。C、D：放疗（radiotherapy, RT）后2个月。T2加权成像（C）、T1加权增强成像（D）。该组影像显示病灶完全缓解，对比强化影完全消失。 图b 右侧梨状叶胶质瘤。A、B：治疗前T2加权成像（A）、T1加权增强成像（B），病灶无对比强化表现。C、D：放疗后2个月。T2加权成像（C）、T1加权增强成像（D）。根据非增强型肿瘤实体瘤疗效评价标准（Response Evaluation Criteria in Solid Tumors, RECIST），该组影像显示病灶呈部分缓解/疾病稳定状态，T2加权成像高信号范围较前缩小。 图c 左侧梨状叶胶质瘤。A、B：治疗前T2加权成像（A）、T1加权增强成像（B）。C、D：放疗后4个月。T2加权成像（C）、T1加权增强成像（D）。该组影像显示病灶呈部分缓解，仍存在弥漫性对比强化（点状箭头标示）。