MRI dataset evaluating the effect of head down tilt 15° on cerebral perfusion in acute ischemic experimental stroke

This dataset contains MRI associated with the following publication, currently submitted to Stroke.

Title: Head down tilt 15° increases cerebral perfusion before recanalization in acute ischemic stroke due to large vessel occlusion. A pre-clinical MRI study
Authors: Simone Beretta, Davide Carone, Tae-Hee Cho, Martina Viganò, Susanna Diamanti, Jacopo Mariani, Francesco Pedrazzini, Elisa Bianchi, Cristiano Pini, Radu Bolbos, Marlene Wiart, Carlo Ferrarese, Fabien Chauveau
Preregistration: preclinicaltrials.eu, identifier PCTE0000198

Raw data:

MRI for 28 adult male Wistar rats (ILAR code Crl:WI(Han); RRID:RGD_2308816)
Magnetic field: 7T
Anesthesia: isoflurane
Time points (in hours, following occlusion): H0 (during MCA occlusion); H24 (after reperfusion)
Ethics statement: agreement numbers APAFIS#15529-2018061512184831v2 and 32924-2021091015062327v4 from local committee CELYNE-CNREEA (C2EA-42, Lyon, France)

Derivatives:

Time-to-Peak (TTP) maps calculated from DSC-PWI
Matlab code used for TTP calculation
Excel files describing the experimental series and the main results

Notes:

No specification is available for Dynamic-Susceptibility-Contrast Perfusion-Weighted-Imaging (DSC-PWI), so the corresponding files are labelled in .bidsignore
R10 had no anatomical T2w on H0
H24 session could not be performed for 8 animals (R03-R10-R26-R28-R29-R31-R33-R34)
R28 was not positioned properly during the first run of DSC-PWI, positioning was corrected for the second run

This dataset has been converted using BrkRaw (v0.3.7) on 2024-01-23.
## How to cite?
- https://doi.org/10.5281/zenodo.3818615