Epigenetic Repogramming by an Environmental Carcinogen Through Chromatin Domain Disruption [RNA-Seq]

ChEBI2014-09-26 更新2026-07-21 收录

环境致癌物毒理机制

表观遗传重编程

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-56052 数据链接链接失效反馈

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Epigenetic Repogramming by an Environmental Carcinogen Through Chromatin Domain Disruption [RNA-Seq]

创建时间：

2014-09-26

MERVL/Zscan4 network activation results in transient genome-wide DNA demethylation of mESCs. Mus musculus

表观遗传重编程

干细胞内源性逆转录病毒调控

Mouse embryonic stem cells are heterogeneous and contain rare cells expressing transcripts normally upregulated in pre-implantation embryos, including the Zscan4 cluster and MuERVL endogenous retrovir

NIAID Data Ecosystem110

Epigenetic reprogramming through KDM6B drives immunofibroblast early commitment and immune properties [CUT&RUN-seq]

表观遗传重编程

免疫纤维母细胞分化

TLS are composed of immune cells, including lymphocytes and myeloid cells, lymphatic and blood endothelial cells, and PDPN+ stromal cells with lymphoid stromal cells (LSC) features called immunofibrob

NIAID Data Ecosystem50

Supporting code and data for Tan et al 2024: Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation

表观遗传重编程

甲基化调控基因

In mammals, global passive demethylation contributes to epigenetic reprogramming during early embryonic development. At this stage, the majority of DNMT1 protein are excluded from nucleus, which are c

Figshare2024-08-05 更新40

Cell fusion-mediated pluripotent reprogramming triggers ordered changes in chromatin and gene expression across the human inactive X chromosome. Cell fusion-mediated pluripotent reprogramming triggers ordered changes in chromatin and gene expression across the human inactive X chromosome

表观遗传重编程

X染色体再激活

Erasure of epigenetic memory is required to convert somatic cells towards pluripotency. Reactivation of the inactive X chromosome (Xi) has been used to model epigenetic reprogramming in mouse, but hum

NIAID Data Ecosystem70

Active and Passive Demethylation of Male and Female Pronuclear DNA in the Mammalian Zygote

受精卵DNA去甲基化

表观遗传重编程

The epigenomes of mammalian sperm and oocytes, characterized by gamete-specific 5-methylcytosine (5mC) patterns, are reprogrammed during early embryogenesis to establish full developmental potential.

NIAID Data Ecosystem50

Epigenetic Repogramming by an Environmental Carcinogen Through Chromatin Domain Disruption [RNA-Seq]

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