Concise and Efficient Synthesis of Indole–Indolone Scaffolds through MeOTf-Induced Annulation of N‑(2-Cyanoaryl)indoles
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MeOTf-triggered annulation of N-(2-cyanoaryl)indoles to provide indolo[1,2-a]indol-10-imines and the corresponding indolo[1,2-a]indol-10-ones have been described under metal-free conditions. A variety of functional groups are tolerated in their scaffolds with good to excellent yields. The reaction could be carried to gram scale.
创建时间：
2019-10-29
