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Hmgb2 improves astrocyte to neuron conversion by increasing the chromatin accessibility of genes associated with neuronal maturation in a proneuronal factor-dependent manner

NIAID Data Ecosystem2026-05-02 收录

星形胶质细胞-神经元转化

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数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE240860 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2025-04-23

免疫稳态

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Intestinal macrophages (IMs) are uniquely programmed to tolerate exposure to bacteria without mounting potent inflammatory responses. The cytokine IL-10 maintains the macrophage anti-inflammatory resp

NIAID Data Ecosystem70

Chromatin accessibility profiling of LSK cells with hyperactivated Notch1 and/or Tcf7 knock-out [ATAC-seq_mouse]. Chromatin accessibility profiling of LSK cells with hyperactivated Notch1 and/or Tcf7 knock-out [ATAC-seq_mouse]

淋巴细胞白血病表观遗传学

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NOTCH1 is a well-established lineage specifier for T cells and amongst the most frequently mutated genes throughout all subclasses of T cell acute lymphoblastic leukemia (T-ALL). How oncogenic NOTCH1

NIAID Data Ecosystem50

ATAC-seq data in project that HMGA2 protects hematopoietic stem cell and drives the self-renewal division in stress condition

干细胞应激响应

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Hematopoietic stem cell (HSC) respond to various stresses and produce mature blood cells; however, it is not clear how HSCs maintain and restore hematopoiesis by determining their self-renewal and dif

NIAID Data Ecosystem40

干细胞衰老

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Tissue homeostasis requires long-term lineage fidelity of somatic stem cells. Whether and how age-related changes in somatic stem cells impact the faithful execution of lineage decisions remains large

NIAID Data Ecosystem60

XAF1 promotes the innate immune response against RNA viruses by regulating chromatin accessibility

先天免疫反应

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XAF1 promotes the innate immune response against RNA viruses by regulating chromatin accessibility

integrated proteome resources50