Data from: Effect on electrospun fibers by synthesis of high branching poly-lactic (PLA)

Poly-lactic electrospun porous fibers have been widely used in tissue engineering scaffolds. However, the application of linear Poly-lactic is limited due to its poor hydrophilicity, which leads to phase separation and has been seldom used in porous fiber preparation. Instead, using of branching Poly-lactic acts as a new effective method to prepare porous fibers because it can increase Poly-lactic polar property and make it easy to be formulated in the following application. In current study, we prepared an ultra-high molecular weight of high branching Poly-lactic with glycerol as the initiator by controlling the ring-opening polymerization time, adding amount of catalyst and glycerol. The structure, molecular weight and thermal properties of copolymers were tested subsequently. The result showed that the surface of the high branching Poly-lactic films is smooth, hydrophilic and porous. This branching Poly-lactic formed electrospun porous fibers, possessed a strong adsorption of silver ion. Comparing with the application of linear Poly-lactic and 3-arm Poly-lactic materials, our study provided a simple and efficient way to synthesize branching Poly-lactic polymer and prepare electrospun porous fibers, which may provide potential applications in the field of biomaterials for tissue engineering or antibacterial dressing.聚乳酸（Poly-lactic）静电纺丝多孔纤维已被广泛应用于组织工程支架领域。然而，线性聚乳酸由于亲水性较差，且易发生相分离，其应用受到极大限制，因此极少被用于多孔纤维的制备。与之相反，采用支化聚乳酸（branching Poly-lactic）制备多孔纤维是一种新型高效方法，因其可提升聚乳酸的极性，便于后续应用中的配方调控。本研究以甘油为引发剂，通过调控开环聚合反应时长、催化剂及甘油的添加量，制备了超高分子量高支化聚乳酸。随后对该共聚物的结构、分子量及热性能进行了表征测试。结果表明，高支化聚乳酸薄膜表面光滑、亲水性良好且具有多孔结构。该支化聚乳酸可制备得到静电纺丝多孔纤维，且对银离子具有较强的吸附能力。相较于线性聚乳酸与三臂聚乳酸（3-arm Poly-lactic）材料的应用场景，本研究提供了一种简便高效的支化聚乳酸合成方法，可用于制备静电纺丝多孔纤维，有望在组织工程生物材料或抗菌敷料领域实现潜在应用。