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Pharmacological profiles of YHS within G protein coupled receptors (GPCRs).

Figshare2016-09-14 更新2026-04-29 收录

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https://figshare.com/articles/dataset/Pharmacological_profiles_of_YHS_within_G_protein_coupled_receptors_GPCRs_/3828015 数据链接链接失效反馈

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Pharmacological profiles of YHS within G protein coupled receptors (GPCRs).

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2016-09-14

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Targeting G protein-coupled receptors (GPCRs) through allosteric sites offers advantages over orthosteric sites in identifying drugs with increased selectivity and potentially reduced side effects. In

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Targeting gamma-glutamyltransferase 1 on myeloid-derived suppressor cells prevents tumor progression caused by G-CSF in neutropenic mouse model

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Myeloid-derived suppressor cells (MDSCs) are one of the major immunosuppressive cells that accumulate in tumor-bearing hosts. Since MDSCs suppress anti-tumor immunity and promote tumor progression, th

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Selective Fluorescent Nonpeptidic Antagonists For Vasopressin V 2 GPCR: Application To Ligand Screening and Oligomerization Assays.

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A series of fluorescent benzazepine ligands for the arginine–vasopressin V2 receptor (AVP V2R) was synthesized using “Click” chemistry. Their in vitro pharmacological profile at AVP V2R, V1aR, V1bR, a

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Pharmacological profiles of YHS within G protein coupled receptors (GPCRs).

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