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A PGC-1alpha-dependent decrease in mitochondrial oxidative metabolism in muscle of humans with inherited insulin resistance

ChEBI2014-02-17 更新2026-07-21 收录

线粒体代谢

胰岛素抵抗机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-36297 数据链接链接失效反馈

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A PGC-1alpha-dependent decrease in mitochondrial oxidative metabolism in muscle of humans with inherited insulin resistance

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创建时间：

2014-02-17

早产儿微生物组

胰岛素抵抗机制

Preterm children are at increased risk of insulin resistance, obesity, and cardiovascular disease. We hypothesise that adverse early life events in preterm children may lead to alterations in the gut

NIAID Data Ecosystem60

ABCA7 deficiency causes neuronal dysregulation by altering mitochondrial lipid metabolism

阿尔茨海默病机制

线粒体代谢

ABCA7 loss-of-function variants are associated with increased risk of Alzheimer's disease (AD). Using ABCA7 knockout human iPSC models generated with CRISPR/Cas9, we investigated the impacts of ABCA7

NIAID Data Ecosystem20

Transcription profiling of muscle cells in mice at different different time points following muscle and normal diets to study insulin resistance and obesty

肌肉代谢转录组学

胰岛素抵抗机制

Transcription profiling of muscle cells in mice at different different time points following muscle and normal diets to study insulin resistance and obesty

ChEBI2013-01-30 更新10

The Ccr4-Not complex regulates TORC1 signaling and mitochondrial metabolism by promoting vacuole V-ATPase activity. The Ccr4-Not complex regulates TORC1 signaling and mitochondrial metabolism by promoting vacuole V-ATPase activity

TOR信号通路调控

线粒体代谢

The Ccr4-Not complex is an effector of multiple signaling pathways controlling gene transcription and mRNA turnover. Herein, we provide evidence that Ccr4-Not also activates nutrient signaling through

NIAID Data Ecosystem30

Maximum proton leak capacities (state IV+) as a putative fraction of total mitochondrial state III respiration (complex I and II, liver) in N. rossii and L. squamifrons.

线粒体代谢

鱼类生理学

Values are given as means ± SEM over all assay temperatures (0, 6, 12°C) of control/acclimated N. rossii (control: 1°C, 0.04 kPa CO2, n = 9; warm normocapnic: 7°C, 0.04 kPa CO2, n = 5; cold hypercapni

Figshare2015-12-02 更新20

A PGC-1alpha-dependent decrease in mitochondrial oxidative metabolism in muscle of humans with inherited insulin resistance

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