Enzalutamide (ENZ) is a potent androgen receptor (AR) antagonist with activity in castration-resistant prostate cancer (CRPC); however, progression to ENZ-resistant (ENZ-R) CRPC frequently occurs with
Evaluation of the effect of 3 ASOs targeting FXN on mRNA levels Overall design: PolyA RNA seq for ASOs targeting the Frataxin gene. Single-end 75 cycles, 3 replicates per treatment.
Aberrant alternative splicing of mRNAs results in dysregulated gene expression in multiple neurological disorders. Here we show that hundreds of mRNAs are incorrectly expressed and spliced in white bl
African Americans develop end-stage renal disease at a higher rate compared to European Americans due to two polymorphisms (G1 and G2 risk variants) in the apolipoprotein L1 (APOL1) gene that are comm
The North America Oligonucleotide Therapeutics Drug market report offers a thorough competitive analysis, mapping key players’ strategies, market share, and business models. It provides insights into