Identifying actionable targets through integrative analyses of GEM model and human prostate cancer profiling [Agilent]. Mus musculus

Here we prolife prostate cancers derived from GEM models of prostate cancer representative of human prostate cancer Overall design: Total DNA was isolated from established prostate cancers in 4 GEM models of prostate cancer - PB-MYC, Pten-/-, Pten-/- p53-/-, Pten-/- Rosa26-ERG, and 3 cell lines derived from GEM models including CaP8, MYC CaP, and MPC3 and normalized to wild-type prostate of litter-mate mice of same genetic background strain