Analysis of TC-mAb mice (Exp1: early B cell development)
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The experiment had been performed to analyze early B cell development of human antibody-procducing mice (TC-mAb mice). The flow cytometry experiment was designed to detect the subsets of Pro-B/ Pre-B (IgM-B220+), immature B (IgM+B220+), and mature recirculating B (IgMlo/+B220hi) cells in bone marrow.
Notes:
This experiment corresponds to Figure 7a and Supplementary Figure 15-16 in the paper "Efficient human-like antibody repertoire and hybridoma production in trans-chromosomic mice carrying megabase-sized human immunoglobulin loci". Publication link: https://doi.org/10.21203/rs.3.rs-103241/v1
创建时间:
2022-03-01



