Integrated transcriptome and metabolome analysis of mechanism on intranasal spray insulin against vascular dementia. Integrated transcriptome and metabolome analysis of mechanism on intranasal spray insulin against vascular dementia

to investigate the effects and mechanism of insulin on 2-VO induced vascular dementia (VD) rat models. We then performed gene expression profiling analysis using data obtained from RNA-seq of 3 different groups. Overall design: Comparative gene expression profiling analysis of RNA-seq data for hippocampus in CK, VD and INS+VD groups.