Regional Chemotherapy with Intrahepatic Irinotecan Beads for patients with Livermetastatic Colorectal Cancer.

Primary objectives: To investigate the effect of drug eluting bead with irinotecan-trans arteriel chemoembolizatin, administered in combination with FOLFOX and bevacizumab, followed by standard treatment with FLIRI and bevacizumab in patients with liver-only metastatic CRC . Primary endpoints: Frequency of surgical resection and / or RFA treatment.