Crystal structure of checkpoint kinase 2 in complex with PV788

Crystal structure of checkpoint kinase 2 in complex with PV788 Descriptor: N-{4-[(1E)-N-CARBAMIMIDOYLETHANEHYDRAZONOYL]PHENYL}-1H-INDOLE-3-CARBOXAMIDE, NITRATE ION, SERINE/THREONINE-PROTEIN KINASE CHK2 Authors: Lountos, G.T, Jobson, A.G, Tropea, J.E, Self, C.R, Pommier, Y, Shoemaker, R.H, Zhang, G, Waugh, D.S. Deposit date: 2011-03-16 Release date: 2011-11-16 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structural Characterization of Inhibitor Complexes with Checkpoint Kinase 2 (Chk2), a Drug Target for Cancer Therapy. J.Struct.Biol., 176, 2011结合PV788的检查点激酶2（Checkpoint Kinase 2, CHK2）的晶体结构 描述：N-{4-[(1E)-N-氨基甲酰亚胺酰基乙烷肼羰基]苯基}-1H-吲哚-3-甲酰胺、硝酸根离子、丝氨酸/苏氨酸蛋白激酶CHK2 作者：Lountos, G.T.、Jobson, A.G.、Tropea, J.E.、Self, C.R.、Pommier, Y.、Shoemaker, R.H.、Zhang, G.、Waugh, D.S. 存放日期：2011-03-16 发布日期：2011-11-16 最后修改日期：2023-12-20 实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.35 Å 引用：《检查点激酶2（CHK2，癌症治疗药物靶点）抑制剂复合物的结构表征》，《J. Struct. Biol.》，2011年，第176卷