Data from: De novo sequencing and assembly of Azadirachta indica fruit transcriptome
收藏资源简介:
Azadirachta indica (neem) is a unique, versatile and important tree species. Many parts of the plant are traditionally used as pesticide, insecticide, fungicide and for other medicinal purposes. Azadirachta fruits and seeds, a good source of oil, are widely used for agriculturally important pest management. Neem oil and its derivatives also support multiple cottage industries in India. Past efforts have been mostly concentrated towards identifying, characterizing and synthesizing one of its principal components, i.e. azadirachtin from seed kernels. Despite diverse use of the neem plant, a modern drug-development programme which systematically exploits the therapeutic ability of Azadirachta fruits remains to be fully established. Next generation sequencing technology that helps decode genomes and transcriptomes has transformational impact on medicine, agriculture, bio-fuel and biodiversity studies. Here, we report sequencing, assembly and analysis of Azadirachta fruit transcriptome using next-generation sequencing technology. We believe that our study shall offer valuable insights towards realizing the larger vision of understanding the key medicinally active compounds and their pathways.
印楝(Azadirachta indica,俗称neem)是一种独特、多用途且极具重要性的树种。该植物的多个部位在传统实践中被用作农药、杀虫剂、杀菌剂,亦可用于多种医疗用途。印楝的果实与种子是优质油脂来源,被广泛应用于农业领域重要的害虫防治工作。印楝油及其衍生物也为印度众多家庭手工业提供了产业支撑。过往研究大多集中于从种子仁中鉴定、表征并合成其主要活性成分之一——印楝素(azadirachtin)。尽管印楝植物的应用场景多样,但一套能够系统性挖掘印楝果实治疗潜力的现代化药物开发项目仍有待全面建立。可用于解析基因组与转录组的下一代测序技术(next generation sequencing)对医学、农业、生物燃料及生物多样性研究具有变革性推动作用。本研究采用下一代测序技术,完成了印楝果实转录组的测序、组装与分析工作。我们相信本研究将为实现解析关键药用活性成分及其合成通路的宏大愿景提供极具价值的学术见解。



