Gene expression and chromatin accessibility profile at single cell level of B16 cells [B16_D0_3_5_scMulti]

B16 F10 is a depigmented mouse melanoma cell line which is considered as a homogeneous cell population. These cells when cultured at a very low density of 100 cells/cm2 starts to pigment progressively. We used single nucleus RNA+ATAC sequencing (scMultiomics) to analyze the transciptional diversity and to investigate the epigenetic basis of this diversity of day 0, 3 and 5 B16 cells cultured at low density. Overall design: B16 F10 cells were cultured at a very low density of 100 cells/cm2 for 3 or 5 days. Cells cultured at high density and used to setup low density cultures were taken as day 0 sample.