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Effect of TLR7/8 dual agonist 3M-052 on B cell response to melanoma

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE190261
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资源简介:
B cells potentially play a role in the immune response to melanoma, including during treatment with immune modulators. We profiled effects of 3M-052 on gene expression in draining lymph nodes of syngeneic mice bearing B16 melanoma tumors. When B16 tumors reached 30-40 mm2 in size, they were injected intratumorally once with 3M-052 or vehicle control. Draining lymph nodes from 4 mice in each group (3M-052 vs. control) were harvested 4 days after intratumoral injection of 3M-052 or control.
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2022-03-02
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