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An early, novel arginine methylation of KCa3.1 attenuates subsequent T cell exhaustion.

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NIAID Data Ecosystem2026-05-02 收录
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We identified changes in the protein arginine methylome during the initial 30 min of TCR engagement and discovered a novel arginine methylation of a Ca2+ -activated potassium transporter, KCa3.1, which regulates Ca2+ -mediated NFAT1 signaling to ensure optimal activation.

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2025-05-29
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