Gene expression profiles of high and low immune responder Holstein cows

The study explores the genetic basis of high or low antibody (Ab) and cell (DTH)-mediated immune responses in Canadian Holstein cows using microarray hybridization to an in-house immune-endocrine cDNA microarray Keywords: immune response comparison The study uses a common reference design for the microarray hybridizations. There are three biological replicates per group and there are four groups: high-Ab, low-Ab, high-DTH and low DTH. The design included four technical replicates with dye swap for each biological replicate.