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Inhibition of ketohexokinase C isoform impairs the development of PDAC tumors

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NIAID Data Ecosystem2026-05-01 收录
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the genetic inactivation of Khk-C enhanced the survival of KPC-driven PDAC model even in absence of high fructose diet. Moreover Khk-C knock out decreased the viability of KPC organoids and cancer cells, the migratory capability of PDAC cells in vitro and the growth of KPC cells in vivo in a cell autonomous manner.

创建时间:
2023-10-13
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