Purpose: Study the changes in the transcriptome of metastatic melanoma PDX cells upon combination treatment with AURKA and MEK inhibitors Methods: RNAseq analysis of melanoma PDX cells treated with AU

NIAID Data Ecosystem00

Treatment of Rosacea with Isoxanthohumol. Mus musculus

酒渣鼻动物模型

药物转录组学

A mouse model of rosacea was constructed, treated with isoxanthohumol, and skin specimens were collected for sequencing.

NIAID Data Ecosystem00

Microarray Expression Profiling of Punicalagin, Myricetin and Quercetin Treated Leukemia Cell Line (THP-1)

药物转录组学

白细胞基因表达

THP-1 monocyte were differentiated to macrophage using PMA for 24 hrs, then (THP-1) macrophage were treated with DMSO, Punicalagin, Myricetin or Quercetin for 24 hrs. Transcriptional expression profil

NIAID Data Ecosystem00

RNA-seq of cells in Mus musculus nasal turbinates with or without 7DW8-5 treatment. RNA-seq of cells in Mus musculus nasal turbinates with or without 7DW8-5 treatment

药物转录组学

免疫调节研究

Total RNA from cells in nasal turbinate was extracted with miRNeasy micro kit (Qiagen, 217084) according to the manufacturer’s instructions. ERCC RNA Spike-In Mix kit (ThermoFisher Scientific, 4456740

NIAID Data Ecosystem00

Polyphyllin H causes difference in U251MG

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