Mitochondrial Metabolic Reprogramming along with NRF2/KEAP1-mediated Antioxidant Mechanisms Drive Temozolomide Resistance in Glioblastoma Multiforme

The repository contains three main files: (1) a .zip folder with the raw chromatograms from the experiments (blank samples, qualitative control, and samples); (2) the retention index file for matabolite annotation (Alkanes-Retention-index.txt); and (3) an Excel file reporting the extracted intensities, quant mass, spectral similarities, putative annotations, metabolite spectra, and all statistical outputs (PCA, OPLS-DA, t-Test, Volcano Plot data, enrichment analysis etc.).本数据集存储库包含三个主要文件：(1) 一个压缩文件夹，内含实验产生的原始色谱图，涵盖空白样本、定性质控样本与实验样本；(2) 用于代谢物注释的保留指数文件（Alkanes-Retention-index.txt）；(3) 一份Excel表格，记录了提取强度、定量离子质量、谱图相似度、推定代谢物注释、代谢物质谱图，以及所有统计分析结果，包括主成分分析（PCA）、正交偏最小二乘判别分析（OPLS-DA）、t检验、火山图数据、富集分析等。