*defined as high-level resistance to at least one agent from the class. **defined as follows: First-line: no known history of resistance to any agent, and maximum change of 1 class of drugs. Second-li

NIAID Data Ecosystem30

Patterns of predicted relative NRTI susceptibility profiles for 35,377 viruses in HIVDB with 4,749 Distinct NRTI-Resistance patterns * .

HIV耐药性

NRTI易感性预测

Patterns of predicted relative NRTI susceptibility profiles for 35,377 viruses in HIVDB with 4,749 Distinct NRTI-Resistance patterns*.

NIAID Data Ecosystem30

Correlation between the phenotypic drug susceptibility and low frequency variants in Taiwanese CRF07_BC early epidemic isolates.

HIV耐药性

低频变异与表型关联

Correlation between the phenotypic drug susceptibility and low frequency variants in Taiwanese CRF07_BC early epidemic isolates.

NIAID Data Ecosystem40

Computational study of protein specificity: The molecular basis of HIV-1 protease drug resistance

药物设计

HIV耐药性

Drug resistance has sharply limited the effectiveness of HIV-1 protease inhibitors in AIDS therapy. It is critically important to understand the basis of this resistance for designing new drugs. We ha

PubMed Central2001-12-18 更新30

Combining Mutations in HIV-1 Protease to Understand Mechanisms of Resistance

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