DATASET FOR FACTOR V LEIDEN IN SUBJECTS WITH PREECLAMPSIA
收藏Mendeley Data2025-01-01 更新2026-04-09 收录
下载链接：
https://data.mendeley.com/datasets/zvbbtby75p/4
下载链接
链接失效反馈官方服务：
资源简介：
In Ghana, there is limited information regarding factor V Leiden polymorphism on the pathogenesis of preeclampsia (PE) and its associated outcomes; hence, the focus of the current study. Eighty-one (81) consented subjects were recruited after ethical clearance was obtained and structured questionnaire administered to them. Routine blood chemistry and characterization of Factor V Leiden were obtained for subjects. We found FVL mutation much more in PE and hypertensive patients. FVL exon 10 were 0.67 and 0.33 for G and A alleles respectively. There was an absence of FVL mutation in exon 8 in the current study. Increased white blood cells, increased uric acid and a three – fold increment of AST / ALT ratio were observed among PE cases when stratified by FVL exons (exon 8 and 10). This study was the first to report baseline FVL genotypic and allelic frequencies as well as relating clinical variables with it.
提供机构：
Clinical Documentation Specialist, Culver State, California; University of Ghana School of Medicine and Dentistry, Physiology Department, Korle-Bu, Accra; KNUST, Kumasi, Ghana; University of Ghana, Biochemistry Department, Legon, Accra; University of Ghana School of Medicine and Dentistry, Obstetric and Gynecology, Korle-Bu Accra; Regent University of Science and Technology, Allied Health, Accra; National Diabetes Research Center, Korle-Bu, Accra; University of Ghana School of Medicine and Dentistry, Medical Biochemistry, Korle-Bu, Accra; Korle-Bu Teaching Hospital, Child Health, Accra
创建时间：
2025-01-01
