Ring Opening/C–N Cyclization of Activated Aziridines with Carbon Nucleophiles: Highly Diastereo- and Enantioselective Synthesis of Tetrahydroquinolines
收藏Figshare2016-02-23 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Ring_Opening_C_N_Cyclization_of_Activated_Aziridines_with_Carbon_Nucleophiles_Highly_Diastereo_and_Enantioselective_Synthesis_of_Tetrahydroquinolines/2622254
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资源简介：
A simple strategy for the synthesis of substituted tetrahydroquinolines through regio- and stereoselective ring opening of N-tosyl aziridines with carbon nucleophiles generated from 2-(bromoaryl)acetonitriles followed by palladium-catalyzed intramolecular C–N cyclization is reported in excellent yields (up to >99%) and stereoselectivity (ee and de up to >99%).
创建时间：
2016-02-23
