PV-INPATIENT

Reporting adverse drug reactions (ADRs) by patients may contribute to the improvement of drug safety. Thence, we evaluated Turkish inpatients’ knowledge, attitude, and practice regarding pharmacovigilance in a university hospital in Turkey. An observational, cross-sectional study was performed by a face-to-face questionnaire in 260 inpatients. The mean score of knowledge level (1.38 ± 0.12) was far below that of maximum score (15 points). Although 245 of 260 inpatients (94.62%) were aware of side effects, only 18 of them (6.92%) had heard about the pharmacovigilance term and the Turkish Pharmacovigilance Center. Ten of 18 subjects (55.56%) knew that they could directly report ADRs via the reporting form. Forty-two percent of inpatients had experienced ADRs in the past, 69.16% of them preferred to consult the doctor of concern, stopping the drug being the most selected intervention (60.75%). Solely 11.11% of those who were aware of Turkish Pharmacovigilance Center (n=18) reported ADRs to the center. The knowledge, attitude, and practice of Turkish inpatients about pharmacovigilance is insufficient and should be stimulated via several ways to increase the rate of spontaneous reporting of ADRs and to ensure more sensitive attitude.患者报告药品不良反应（Adverse Drug Reactions，ADRs）有助于提升药物安全监管水平。据此，我们针对土耳其某大学附属医院的住院患者，开展了其关于药物警戒（pharmacovigilance）相关知识、态度与实践行为的评估研究。本研究为观察性横断面研究，通过面对面问卷调查的方式，对260名住院患者进行了调研。 患者的知识水平平均得分为1.38±0.12，远低于满分15分的评分标准。尽管260名患者中有245人（占比94.62%）知晓药物副作用，但仅18人（占比6.92%）听闻过药物警戒这一概念以及土耳其药物警戒中心（Turkish Pharmacovigilance Center）。 在这18名知晓相关信息的患者中，有10人（占比55.56%）了解可通过官方报告表单直接上报ADRs。42%的住院患者曾在既往治疗过程中经历过ADRs，其中69.16%的患者选择咨询主管医师，而停药是最常采用的应对措施（占比60.75%）。 在知晓土耳其药物警戒中心的18名患者中，仅有11.11%曾向该中心上报过ADRs。综上，土耳其住院患者关于药物警戒的知识储备、态度认知与实践行为均存在明显不足，需通过多种途径加以引导与强化，以提升ADRs自发上报率，同时培养更为积极的药物警戒意识。