Short-term effects of Elastase inhibition on human islets protein phosphorylation

To evaluate the short-term effect of elastase inhibition using telaprevir or sivelestat or DMSO on human islets Human islets (N=3) were treated for 10 or 30 minutes with DMSO, telaprevir (1 and 100 µg/ml) or sivelestat (100 µg/ml) to evaluate the changes in phosphorylation levels of proteins using the KAM-1325 phospho antibody microarray (Kinexus).