Association of the frequency of identified genes with p53, PTEN, p16 and EGFR alterations.

a Bold indicates statistically significant values;ITGB1- integrin, beta 1; INPP5A- inositol polyphosphate-5-phosphatase; CPS1 - carbamoyl-phosphate synthetase 1, mitochondrial; PROS1 - protein S (alpha).b NP, number of patients per group;