Scn5a

ENCODES a protein that exhibits ankyrin binding; fibroblast growth factor binding; voltage-gated sodium channel activity involved in cardiac muscle cell action potential; INVOLVED IN brainstem development; cerebellum development; membrane depolarization during cardiac muscle cell action potential; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH brain ischemia; congestive heart failure; arrhythmogenic right ventricular cardiomyopathy (ortholog); FOUND IN intercalated disc; plasma membrane; T-tubule; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil

编码一种具有锚蛋白结合能力的蛋白质；参与成纤维细胞生长因子结合；涉及心肌细胞动作电位中电压门控钠通道活性；参与脑干发育、小脑发育；心肌细胞动作电位期间的膜去极化；参与阿替洛尔药理学通路；参与肾上腺素能β受体激动剂和β-阻滞剂药理学通路；参与胺碘酮药理学通路；与脑缺血、充血性心力衰竭、致心律失常性右心室心肌病（同源物）相关；存在于闰盘、质膜、T小管中；与2,3,7,8-四氯二苯并-对-二氧杂蒽、4,4'-磺酰二苯酚、6-丙基-2-硫尿嘧啶相互作用。