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Crystal structure of human DCAF1 WD40 repeats (Q1250L) in complex with compound 6

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Protein Data Bank Japan2023-10-25 更新2026-06-30 收录
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https://pdbj.org/mine/summary/8oga
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Crystal structure of human DCAF1 WD40 repeats (Q1250L) in complex with compound 6 Descriptor: 1,2-ETHANEDIOL, 5-[1-(4-methoxyphenyl)cyclopropyl]-8-(4-methylpiperazin-1-yl)-2,3-dihydroimidazo[2,1-a]isoquinoline, DDB1- and CUL4-associated factor 1, ... Authors: Schroeder, M, Vulpetti, A, Renatus, M. Deposit date: 2023-03-19 Release date: 2023-06-14 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Discovery of New Binders for DCAF1, an Emerging Ligase Target in the Targeted Protein Degradation Field. Acs Med.Chem.Lett., 14, 2023
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2023-03-19
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