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Diastereoselective Synthesis of Diketopiperazine Bis-α,β-epoxides

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Figshare2016-02-23 更新2026-04-29 收录
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Functionalized diketopiperazines (dioxopiperazines) are an important class of molecules in medicinal chemistry and material science. Herein we report a diastereoselective synthesis of diketopiperazine bis-α,β-epoxides via the oxidation of exocyclic olefins. Although six diastereomers may be formed by this approach, only one or two of them were observed.

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2016-02-23
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