MacroH2A2 knockdown vs control ATAC-seq
收藏NIAID Data Ecosystem2026-05-01 收录
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Self-renewal is a crucial property of glioblastoma cells and is enabled by the choreographed function of chromatin regulators and transcription factors. Identifying targetable epigenetic mechanisms of self-renewal could represent an important step toward developing new and effective treatments for this universally lethal cancer. Here we uncover a targetable epigenetic axis of self-renewal mediated by the histone variant macroH2A2. ATAC-seq of primary glioblastoma cells with macroH2A2 knockdown shRNA or control after 7 days of doxycycline induction
创建时间：
2023-08-25
