Eshqobilov Ozodbek Abdusodiqovich

This article analyzes three major cardiovascular pharmacological groups: beta-blockers, calcium channel blockers and antiarrhythmic agents. It uses an IMRAD narrative review design and connects mechanism of action with clinical significance, safety risks and health-system relevance. The results show that cardiovascular medicines are effective only when their pharmacodynamic profile is matched with disease mechanism, patient phenotype and monitoring needs. Uzbekistan-specific cardiovascular burden indicators are included to demonstrate why rational cardiovascular pharmacotherapy is a major public health issue.