Morphogenesis and regeneration share a conserved core transition cell state program that control lung epithelial cell fate

We isolated and identified a population of Icam1/Nkx2-1 epithelial progenitors harboring a transitional state program remarkably conserved in humans and mice during lung morphogenesis and regeneration Epcam+ or Epcam+Icam1+ cells from E14.5 mouse embroynic lungs are isolated and proceeded to single cell sequencing