Th17 cell plasticity towards a T-bet-dependent Th1 phenotype is required for bacterial control in Staphylococcus aureus infection

Manuscript:Th17 cell plasticity towards a T-bet-dependent Th1 phenotype is required for bacterial control in Staphylococcus aureus infectionBartsch et al. 2022Processed and filtered (meta) scRNA-seq dataFor raw (unfiltered) datasets, seehttps://doi.org/10.6084/m9.figshare.14935458.v2https://doi.org/10.6084/m9.figshare.19355459.v1Mice Genotype:Figure 4: C57BL/6 IL17ACrex Rosa26eYFPx Tbx21wtFigure 5: combined and annotated data from C57BL/6 IL17ACrex Rosa26eYFPx Tbx21flox C57BL/6 IL17ACrex Rosa26eYFPx Tbx21wtOrgan: KidneyCells: FACS-sorted CD45+CD3+CD4+eYFP+Files:1. Bartsch2022_Figure4_Tbx21WT_filtered_count_matrix.csv: (380.65 MB) CSV Data; Matrix; UMI-Counts; columns: annotated barcodes; rows: mice gene symbols2. Bartsch2022_Figure4_Tbx21WT_meta_data.csv: (572.71 kB)CSV Data; Meta Data; columns: barcodes, cluster annotation, pseudotime of lineage Th17->Th1, umap dimension 1, map dimension 23. Bartsch2022_Figure5_combined_Tbx21wt_ko_filtered_count_matrix.csv: (526.34 MB)CSV Data; Matrix; UMI-Counts; columns: annotated barcodes; rows: mice gene symbols4. Bartsch2022_Figure5_combined_Tbx21wt_ko_meta_data.csv:(790.91 kB) CSV Data; Meta Data; columns: barcodes, annotation, origIdent (Tbx21wt vs Tb21ko (see mice genotype)), cluster, umap dimension 1, map dimension 2