List of ORFs with consistent differences (OCDs) between the attenuated strain S19 and the two virulent strains, 2308 and 9–941, but not different within the virulent strains.

*Representative locus from 9–941, S19 or 2308 genomes. The mapping for all three genomes is given in Supplemental Table S4
**Ψ = bp Difference, Δ  = bp Deletion, Θ = bp insertion,FS:Frameshift, PS:prematurestop, other letter indicate aa, the word “yes” or “no” in parenthesis indicates if the change in aa caused change in net charge
***The first character indicates the COG category (see Table 6)