V308E mutant of cytochrome P450 2D6 complexed with thioridazine

Protein Data Bank Japan2023-10-04 更新2026-03-21 收录

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V308E mutant of cytochrome P450 2D6 complexed with thioridazine Descriptor: 10-{2-[(2R)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine, ACETATE ION, Cytochrome P450 2D6, ... Authors: Yang, Y.T, Fujita, K, Wang, P.F, Im, S.C, Pearl, N.M, Meagher, J, Stuckey, J, Waskell, L. Deposit date: 2018-03-20 Release date: 2019-03-27 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.394 Å) Cite: Characteristic conformational changes on the distal and proximal surfaces of cytochrome P450 2D6 in response to substrate binding To Be Published

细胞色素P450 2D6（cytochrome P450 2D6）V308E突变体与硫利达嗪复合物描述物：10-{2-[(2R)-1-甲基哌啶-2-基]乙基}-2-(甲硫基)-10H-吩噻嗪、乙酸根离子、细胞色素P450 2D6…… 作者：Yang, Y.T.、Fujita, K.、Wang, P.F.、Im, S.C.、Pearl, N.M.、Meagher, J.、Stuckey, J.、Waskell, L. 存档日期：2018-03-20 发布日期：2019-03-27 最后修改日期：2023-10-04 实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率2.394 Å）引用文献：《细胞色素P450 2D6结合底物后其远端与近端表面的特征构象变化》，待发表

创建时间：

2018-03-20